Glover, 43, followed a stunning Saturday round of 62 with a two-under-par 68 on Sunday to get the job done at Sedgefield Country Club.
The victory catapulted him up the ranking from 112th to 49th in the FedEx Cup standings, with a number of notable players, including Justin Thomas, Billy Horschel and Adam Scott, all failing to produce the performances needed to prolong their seasons.
Glover had a steady opening to his final round before poor weather drew play to a halt for two hours, with the leaders only having four holes left to play. Henley took the outright lead after the delay with a birdie on the 15th hole but then proceeded to bogey all of the remaining three holes to give Glover a clear route to victory.
A lucky bounce saw Glover's tee shot on 18 ricochets off a police buggy, preventing it from ending up in the pine straws, and he then proceeded to lay up with his second shot before sticking his approach close and holing the par putt to seal the win.
Glover was almost flawless tee-to-green during the week, picking up +3.27 strokes on the field. Eventually proving to be the deciding factor, his approach play was also excellent, with the American gaining +2.16 strokes on the field in the category.
All in all an outstanding week for Lucas, it was a visibly emotional victory for the whole Glover family as they celebrated on the 18th green.
Lucas Glover: WITB 2023 (August)
Driver: Srixon Z785 (9.5 degrees; Fujikura Ventus Blue 7 X)
3-wood: Ping G430 Max (15 degrees; Fujikura Ventus Black 8 X)
5-wood: Ping G430 Max (18 degrees; Fujikura Ventus Black 10 X)
Irons: Srixon ZX5 Mk II (4), Srixon ZX7 Mk II (5-PW) True Temper Dynamic Gold Tour Issue X100 (4-PW)
Wedges: Cleveland RTX 6 ZipCore Tour Rack (52, 56, 60) True Temper Dynamic Gold Tour Issue S400
Putter: L.A.B. Mezz.1 Max
Ball: Golf Pride V55 Cord