Patrick Reed has withdrawn from this week's Northern Trust, the PGA Tour's first Playoffs Series event, due to an ankle injury.
Reed, 31, also withdrew from last week's Wyndham Championship where he was rumoured to have pulled out as a result of tiredness having travelled the best part of 25,000 miles the past eight weeks.
The World No.17 has played in tournaments 10 of the last 13 weeks, and he also went over to compete in the Tokyo Olympics after receiving a late call-up following the withdrawal of Bryson DeChambeau due to a positive Covid test.
Reed landed his ninth career victory on the PGA Tour earlier this January with a five-shot romp at the Farmers Insurance Open, albeit in controversial circumstances following a drop he took in the rough during round three.
Since then, Reed has picked up four top-10 finishes including a tie for ninth at The Masters and solo fifth at the Memorial Tournament.
Reed is currently comfortable in the FedEx Cup race at 22nd in the standings.
The top 125 in the FedEx Cup standings head into the first Playoffs event at the Northern Trust this week. The top 70 after Sunday's play then head into the BMW Championship next week, with the top 30 players progressing into the season finale for the FedEx Cup at the Tour Championship.
Reed is not currently in the top six automatic spots for the US Ryder Cup team this September, however, given his experience and Ryder Cup record down the years you have to believe he will be the easiest of wildcard picks for captain Steve Stricker - despite the fact he does not see eye-to-eye with many of his teammates.